Good long-term glycemic compensation is associated with better trabecular bone score in postmenopausal women with type 2 diabetes

Osteoporosis is an increasingly widespread disease, as well as diabetes mellitus. It is now accepted that osteoporotic fractures are a serious co-morbidity and complication of diabetes. Despite of good bone mineral density in Type 2 Diabetes (T2DM) patients is the fracture risk elevated. It is due t...

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Veröffentlicht in:Physiological research 2019-11, Vol.68 (Suppl 2), p.S149-S156
Hauptverfasser: Jackuliak, P, Kužma, M, Killinger, Z, Payer, J
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Sprache:eng
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Zusammenfassung:Osteoporosis is an increasingly widespread disease, as well as diabetes mellitus. It is now accepted that osteoporotic fractures are a serious co-morbidity and complication of diabetes. Despite of good bone mineral density in Type 2 Diabetes (T2DM) patients is the fracture risk elevated. It is due to reduced bone quality. To determine the effect of glycemic compensation on bone density and trabecular bone score (TBS) in T2DM. We analyzed a cohort of 105 postmenopausal women with T2DM. For all patients, central bone density (spinal and lumbar spine) was tested by DXA methodology, glycemic control parameters were assessed, and anthropometric parameters were measured. Bone quality was analyzed using TBS software. The results were statistically processed. Good glycemic compensation with glycated hemoglobin (A1c) value
ISSN:0862-8408
1802-9973
DOI:10.33549/PHYSIOLRES.934304