Alkaline phosphatase activity of duodenal enterocytes after neonatal administration of monosodium glutamate to rats

Alkaline phosphatase activity of duodenal enterocytes after neonatal administration of monosodium glutamate to rats

In the present work neonatal male and female Wistar rats were treated intraperitoneally with monosodium glutamate (MSG 2 mg/kg b.w.) or saline (controls) daily for 4 day after birth. At the age of 30 and 80 days, the alkaline phosphatase activity (AP) in the brush border of individual enterocytes, t...

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Veröffentlicht in:Physiological research 2000, Vol.49 (2), p.269-277
Hauptverfasser: Mozes, S, Lenhardt, L, Martinková, A
Format: Artikel
Sprache:eng
Schlagworte:
Adipose Tissue - pathology
Aging - metabolism
Alkaline Phosphatase - metabolism
Animals
Animals, Newborn - growth & development
Animals, Newborn - metabolism
Duodenum - cytology
Duodenum - drug effects
Duodenum - enzymology
Enterocytes - enzymology
Female
Injections, Intraperitoneal
Male
Obesity - chemically induced
Obesity - pathology
Organ Size - drug effects
Rats
Rats, Wistar
Reference Values
Sodium Glutamate - pharmacology
Tissue Distribution
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Zusammenfassung:In the present work neonatal male and female Wistar rats were treated intraperitoneally with monosodium glutamate (MSG 2 mg/kg b.w.) or saline (controls) daily for 4 day after birth. At the age of 30 and 80 days, the alkaline phosphatase activity (AP) in the brush border of individual enterocytes, the body fat content and Lee's index of obesity were analyzed. Microdensitometrical quantification of AP was significantly increased on day 30 in males (P
ISSN:0862-8408
1802-9973
DOI:10.33549/physiolres.930000.49.269