Does Vitamin D3 supplementation affect antioxidant enzymes of D3 deficient patients with asthma COPD overlap (ACO)? - A randomized controlled trial

Background: Asthma COPD overlap (ACO) is a new disease entity where respiratory tract is continuously exposed to oxidants. Supplementation of vitamin D3 have shown evidence of increasing antioxidant enzymes level which neutralize these oxidants. Objectives: To evaluate the effects of vitamin D3 supp...

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Veröffentlicht in:Journal of Bangladesh Society of Physiologist 2020-01, Vol.14 (2), p.89-98
Hauptverfasser: Mahmud, Maksuda Bintey, Ali, Taskina, Bennoor, Kazi Saifuddin, Hossain, Md Ali, Rahman, Mustafizur, Khan, Mohammad Abdus Shakur, Islam, Md Saiful, Hassan, Samia, Nahar, Salsa Bil, Rosy, Sharkia Khanam, Sultana, Naznin, Anjum, Salma
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Sprache:eng
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Zusammenfassung:Background: Asthma COPD overlap (ACO) is a new disease entity where respiratory tract is continuously exposed to oxidants. Supplementation of vitamin D3 have shown evidence of increasing antioxidant enzymes level which neutralize these oxidants. Objectives: To evaluate the effects of vitamin D3 supplementation on two antioxidant enzyme levels in D3 deficient ACO patients. Methods: A double blinded placebo controlled randomized clinical trial (RCT) was carried out on 60 (sixty) D3 deficient [serum 25-hydroxycholecalciferol, 25(OH) D
ISSN:1995-1213
DOI:10.3329/jbsp.v14i2.44790