Steroids from the stem of Nymphaea stellata

Three steroids, namely 24-ethyl-5?-cholestan-3-one (1), 5?-stigmast-22-en-3-one (2), stigmast-5, 22-dien-3-one (3) have been isolated from N. stellata. The phytochemical and antimicrobial as well as cytotoxic activities of Nymphaea stellata were investigated in this study. Crude extracts of N. stell...

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Veröffentlicht in:Journal of Bangladesh Academy of Sciences 2013-07, Vol.37 (1), p.109-113
Hauptverfasser: Chowdhury, Badrun Naher, Haque, Md Mozammel, Sohrab, Md Hossain, Afroz, Farhana, Al-Mansur, MA, Sultana, Tamanna, Hasan, Choudhury Mahmood
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Sprache:eng
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Zusammenfassung:Three steroids, namely 24-ethyl-5?-cholestan-3-one (1), 5?-stigmast-22-en-3-one (2), stigmast-5, 22-dien-3-one (3) have been isolated from N. stellata. The phytochemical and antimicrobial as well as cytotoxic activities of Nymphaea stellata were investigated in this study. Crude extracts of N. stellata and various column fractions exhibited poor antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria and fungi. The crude extract and the fractions showed significant cytotoxic effect when subjected to brine shrimp lethality bioassay. DOI: http://dx.doi.org/10.3329/jbas.v37i1.15687 Journal of Bangladesh Academy of Sciences, Vol. 37, No. 1, 109-113, 2013
ISSN:0378-8121
DOI:10.3329/jbas.v37i1.15687