Synthesis and Characterization of New Pyrazolopyrimidine Derivatives Incorporated to Benzothiaazole
Reaction of 2-Amino-6-methyl benzothiazole with 1-cyano-acetyl-3,5-dimethylpyrazole afforded cyanoacetamide derivative (2). Compound 2 was used as the precursor for the synthesis of novel aminopyrazole derivative (5) by reaction with phenyl isothiocyanate and methyl iodide followed by addition of hy...
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Veröffentlicht in: | Letters in Applied NanoBioScience 2021-09, Vol.10 (3), p.2429-2437 |
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Reaction of 2-Amino-6-methyl benzothiazole with 1-cyano-acetyl-3,5-dimethylpyrazole afforded cyanoacetamide derivative (2). Compound 2 was used as the precursor for the synthesis of novel aminopyrazole derivative (5) by reaction with phenyl isothiocyanate and methyl iodide followed by addition of hydrazine hydrate. Treatment of aminopyrazole (5) with different reagents gave pyrazolopyrimidine derivatives (7-12). The newly synthesized compounds were characterized by elemental analysis and the use of spectral data (IR, 1H NMR, and MS). |
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ISSN: | 2284-6808 2284-6808 |
DOI: | 10.33263/LIANBS103.24292437 |