METAL COMPLEXES OF SCHIFF BASE DERIVED FROM 4- (DIETHYLAMINO) SALICYLDEHYDE WITH ANILINE: CHARACTERIZATION, COMPUTATIONAL ANALYSIS, AND ANTIBACTERIAL ACTIVITY STUDY

A biologically active Schiff base derived from 4-(diethylamino)salicylaldehyde with aniline and its Zn(II), Cd(II), Sn(II), and Pb(II) complexes have been synthesized and characterized by various physicochemical techniques. The structure optimization by computational analysis supports the geometry of the metal complexes. The Schiff base existed as a bidentate ligand bonded to the metal ion through the deprotonated phenolic oxygen and the azomethine nitrogen forming neutral ML2 metal chelates. The synthesized ligand and their metal complexes have been screened at three different concentrations and compared for their antibacterial action against bacterial species Streptococcus, Staph, Staphylococcus aureus, and Escherichia coli. The result shows that the metal complexes are more bioactive than ligands.