Inhibitory Effect of Selenium on Esophagus Cancer Cells and the Related Mechanism

Inhibitory Effect of Selenium on Esophagus Cancer Cells and the Related Mechanism

Selenium has been associated with many malignant tumors including esophagus cancer (EC). In current study, we examined the effects of three types of selenium, sodium selenite (SSE), methylseleninic acid (MSA) and methylselenocysteine (MSC) on EC cell line Eca109. Here, selenium attenuated cell viabi...

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Veröffentlicht in:Journal of Nutritional Science and Vitaminology 2020/10/31, Vol.66(5), pp.456-461
Hauptverfasser: LIU, Tao, SUN, Yu, YANG, Shengzhuang, LIANG, Xiangsen
Format: Artikel
Sprache:eng
Schlagworte:
apoptosis
cell proliferation
methylseleninic acid
methylselenocysteine
sodium selenite
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Zusammenfassung:Selenium has been associated with many malignant tumors including esophagus cancer (EC). In current study, we examined the effects of three types of selenium, sodium selenite (SSE), methylseleninic acid (MSA) and methylselenocysteine (MSC) on EC cell line Eca109. Here, selenium attenuated cell viability and increased cell apoptosis, especially in MSC, when compared with control group (p
ISSN:0301-4800
1881-7742
DOI:10.3177/jnsv.66.456