Increases in Gastric Histidine Decarboxylase Activity and Plasma Gastrin Level in Streptozotocin-induced Type 1 Diabetic Rats

When type 1 diabetes mellitus was induced in rats by injecting streptozotocin, histidine decarboxylase expression was abnormally up-regulated in a transcriptional level, and 7 d after the injection, the enzyme activity was increased about 3-fold over the control (p

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Nutritional Science and Vitaminology 2000, Vol.46(3), pp.144-148
Hauptverfasser:	INUI, Hiroshi, YASUNO, Rikako, TAKENOSHITA, Makoto, OHNISHI, Yasuyo, SAKAMOTO, Miki, MATSUZAKI, Junko, YAMAJI, Ryoichi, MIYATAKE, Kazutaka, YAMATODANI, Atushi, NAKANO, Yoshihisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Glucose - metabolism Blotting, Northern Diabetes Mellitus, Experimental - chemically induced Diabetes Mellitus, Experimental - enzymology Diabetes Mellitus, Experimental - metabolism Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Gastric Acid - metabolism gastric acid secre-tion Gastric Mucosa - enzymology gastrin Gastrins - blood histidine decarboxylase Histidine Decarboxylase - genetics Histidine Decarboxylase - metabolism Insulin - administration & dosage Intestine, Small - enzymology Kidney - enzymology Liver - enzymology Male Medical sciences Pancreas - enzymology Rats Rats, Wistar Streptozocin type 1 diabetes mellitus Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	When type 1 diabetes mellitus was induced in rats by injecting streptozotocin, histidine decarboxylase expression was abnormally up-regulated in a transcriptional level, and 7 d after the injection, the enzyme activity was increased about 3-fold over the control (p
ISSN:	0301-4800 1881-7742
DOI:	10.3177/jnsv.46.144