Suppressive effect of extract from Phellodendri cortex on the differentiation of 3T3-L1 mouse preadipocytes

Suppressive effect of extract from Phellodendri cortex on the differentiation of 3T3-L1 mouse preadipocytes

The effects of an extract from Phellodendron amurense Ruprecht (Phellodendri cortex) and its component berberine on the differentiation of 3T3-L1 mouse preadipocytes were studied. The extract and berberine suppressed both the accumulation of triglyceride and the activity of glycerol-3-phosphate dehy...

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Veröffentlicht in:Nihon Shokuhin Kagaku Kōgaku kaishi 2005, Vol.52(11), pp.535-537
Hauptverfasser: Shinmoto, H.(National Food Research Inst., Tsukuba, Ibaraki (Japan)), Iwashita, K, Kobori, M, Kimura, T, Yamagishi, K, Suzuki, M
Format: Artikel
Sprache:jpn
Schlagworte:
CELLS
CELLULE
CELULAS
EXTRACTOS VEGETALES
EXTRAIT D'ORIGINE VEGETALE
MICE
PLANT EXTRACTS
RATON
SOURIS
TRIGLICERIDOS
TRIGLYCERIDE
TRIGLYCERIDES
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Zusammenfassung:The effects of an extract from Phellodendron amurense Ruprecht (Phellodendri cortex) and its component berberine on the differentiation of 3T3-L1 mouse preadipocytes were studied. The extract and berberine suppressed both the accumulation of triglyceride and the activity of glycerol-3-phosphate dehydrogenase (GPDH). We concluded that berberine, a component of Phellodendri cortex, plays an important role in the differentiation of adipocytic cells.
ISSN:1341-027X
1881-6681
DOI:10.3136/nskkk.52.535