Terminalia catappa flour extract mitigated monosodium glutamate intoxicated rats’ kidney biofunction and histology

Objective: This study investigated the Terminalia Catappa flour mitigated monosodium glutamate intoxicated rats’ kidney biofunction and histology. Materials and Methods: Twenty-four (24) male albino Wistar rats with mean weight of 120.61±15.15 g were divided into six groups (n=4). Group 1, the normal control group (received distilled water), group II, the negative control (received 8mg MSG/g b.wt), group III, the extract control (received 300 mg extract/kg b.wt), group IV (received 8 mg MSG/g b.wt. + 100 mg extract/kg b.wt.), group V (received 8 mg MSG/g b.wt. + 300 mg kg-1 b.wt. extract) and group VI received 8 mg MSG/g b.wt. + 500 mg extract/kg b.wt). Treatment was administered daily by oral gavage for 14 days. Data were subjected to one-way ANOVA followed by Duncan post-hoc test at p