Lupene-type triterpenic and steroidal constituents from the roots of Streblus asper Lour

Streblus asper Lour. (Moraceae)is a small tree found in tropical regions of the world and used for the treatment of fever, diarrhea, dysentery, elephantiasis, filariasis, gingivitis, leprosy, piles, skin diseases, toothache and wounds.Phytochemical investigation of a methanol extract of the roots led to the isolation of two new compounds characterized as lup-20(29)-en-3β-olyl octadec-9′-enoate (1) and stigmast-5-en-3β-olyl-26-oic acid-3β-hexadecanoate (4) together with the four known constituents identified as lupeol linoleate (2), stigmasterol palmitate (3), cerotic acid (5) and octacosanoic acid (6). The structures of all these compounds were elucidated on the basis spectral data analysis and chemical reactions.