calcium antagonistic effect of the volatile oil of Teucrium polium

Abstract The effect of the volatile oil of Teucrium polium was investigated in vitro using isolated segments of rabbit intestine. The volatile oil was found to inhibit the spontaneous movements of the intestine and the contractions of the intestine induced by depolarization with high potassium (K+)...

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Veröffentlicht in:	International journal of crude drug research 1990, Vol.28 (3), p.201-207
Hauptverfasser:	Aqel, M.B, Gharaibeh, M.N, Salhab, A.S
Format:	Artikel
Sprache:	eng
Schlagworte:	calcium chemical composition intestines ion transport medicinal properties movement plant fats and oils Teucrium polium volatile fatty acids
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Zusammenfassung:	Abstract The effect of the volatile oil of Teucrium polium was investigated in vitro using isolated segments of rabbit intestine. The volatile oil was found to inhibit the spontaneous movements of the intestine and the contractions of the intestine induced by depolarization with high potassium (K+) solution. Also, the volatile oil was found to inhibit 45Ca influx in the intestine in a dose dependent manner. Our results suggest that the volatile oil inhibits Ca2+ influx through the potential dependent Ca2+ channels.
ISSN:	0167-7314 1388-0209 1744-5116
DOI:	10.3109/13880209009082813