Significance of mast cell renal infiltration in patients with anti-GBM nephritis

Significance of mast cell renal infiltration in patients with anti-GBM nephritis

To investigate the role of mast cells (MCs) renal infiltration in the progression of human anti-GBM nephritis, 38 patients diagnosed with anti-GBM nephritis were enrolled. Renal biopsies were performed. Immunohistochemistry was conducted to detect MCs in renal tissues. Patients were divided into gro...

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Veröffentlicht in:Renal failure 2016-07, Vol.38 (6), p.906-913
Hauptverfasser: Wu, Xiao-Mei, Zhang, Yi-Yan, Zhang, Ming-Chao, Zhang, Li-Hua, Zeng, Cai-Hong, Liu, Zhi-Hong, Tang, Zheng
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Anti-GBM nephritis
Anti-Glomerular Basement Membrane Disease - pathology
Chronic Disease
chronic inflammation
chronic lesions
Creatinine - blood
Female
Fibrosis
Humans
Immunohistochemistry
Kidney - pathology
Male
mast cells
Mast Cells - cytology
Middle Aged
Osmotic Pressure
renal function
Retinol-Binding Proteins - urine
Young Adult
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Zusammenfassung:To investigate the role of mast cells (MCs) renal infiltration in the progression of human anti-GBM nephritis, 38 patients diagnosed with anti-GBM nephritis were enrolled. Renal biopsies were performed. Immunohistochemistry was conducted to detect MCs in renal tissues. Patients were divided into group 1 (MCs 
ISSN:0886-022X
1525-6049
DOI:10.3109/0886022X.2016.1164184