Intensification of Peritoneal Dialysis Improves Valacyclovir Neurotoxicity
Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for...
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| Veröffentlicht in: | Renal failure 2013-03, Vol.35 (2), p.289-290 |
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| container_title | Renal failure |
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| creator | Pipili, Chrysoula Pantelias, Kostas Deda, Edmond Tsiamalos, Pandelis Kostis, Evaggelos Grapsa, Eirini |
| description | Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal, our case showed that intensive peritoneal dialysis regimen leads to the recovery of neurotoxicity after 3 days. |
| doi_str_mv | 10.3109/0886022X.2012.743914 |
| format | Article |
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The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. 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The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. 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Pantelias, Kostas ; Deda, Edmond ; Tsiamalos, Pandelis ; Kostis, Evaggelos ; Grapsa, Eirini</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c484t-96cf69393c731d620f8580b351c865705586fd2b4ba0fd13deeca7f1a28af2583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acute Kidney Injury - chemically induced</topic><topic>Acute Kidney Injury - therapy</topic><topic>Acyclovir - adverse effects</topic><topic>Acyclovir - analogs & derivatives</topic><topic>Acyclovir - therapeutic use</topic><topic>Aged</topic><topic>Antiviral Agents - adverse effects</topic><topic>Antiviral Agents - therapeutic use</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Herpes Zoster - diagnosis</topic><topic>Herpes Zoster - drug therapy</topic><topic>Humans</topic><topic>intensification</topic><topic>Kidney Failure, Chronic - diagnosis</topic><topic>Kidney Failure, Chronic - therapy</topic><topic>Kidney Function Tests</topic><topic>life-threatening</topic><topic>neurotoxicity</topic><topic>peritoneal dialysis</topic><topic>Peritoneal Dialysis, Continuous Ambulatory - methods</topic><topic>Risk Assessment</topic><topic>Treatment Outcome</topic><topic>valacyclovir</topic><topic>Valine - adverse effects</topic><topic>Valine - analogs & derivatives</topic><topic>Valine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pipili, Chrysoula</creatorcontrib><creatorcontrib>Pantelias, Kostas</creatorcontrib><creatorcontrib>Deda, Edmond</creatorcontrib><creatorcontrib>Tsiamalos, Pandelis</creatorcontrib><creatorcontrib>Kostis, Evaggelos</creatorcontrib><creatorcontrib>Grapsa, Eirini</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Renal failure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pipili, Chrysoula</au><au>Pantelias, Kostas</au><au>Deda, Edmond</au><au>Tsiamalos, Pandelis</au><au>Kostis, Evaggelos</au><au>Grapsa, Eirini</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intensification of Peritoneal Dialysis Improves Valacyclovir Neurotoxicity</atitle><jtitle>Renal failure</jtitle><addtitle>Ren Fail</addtitle><date>2013-03</date><risdate>2013</risdate><volume>35</volume><issue>2</issue><spage>289</spage><epage>290</epage><pages>289-290</pages><issn>0886-022X</issn><eissn>1525-6049</eissn><abstract>Valacyclovir induced neurotoxicity is a life-threatening complication, usually starting 24-48 h after drug-peak serum concentrations. The elderly with impaired renal function seem to be the most susceptible group to valacyclovir neurotoxicity. Although hemodialysis is considered the best method for rapid drug removal, our case showed that intensive peritoneal dialysis regimen leads to the recovery of neurotoxicity after 3 days.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>23176110</pmid><doi>10.3109/0886022X.2012.743914</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0886-022X |
| ispartof | Renal failure, 2013-03, Vol.35 (2), p.289-290 |
| issn | 0886-022X 1525-6049 |
| language | eng |
| recordid | cdi_crossref_primary_10_3109_0886022X_2012_743914 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Acute Kidney Injury - chemically induced Acute Kidney Injury - therapy Acyclovir - adverse effects Acyclovir - analogs & derivatives Acyclovir - therapeutic use Aged Antiviral Agents - adverse effects Antiviral Agents - therapeutic use Female Follow-Up Studies Herpes Zoster - diagnosis Herpes Zoster - drug therapy Humans intensification Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - therapy Kidney Function Tests life-threatening neurotoxicity peritoneal dialysis Peritoneal Dialysis, Continuous Ambulatory - methods Risk Assessment Treatment Outcome valacyclovir Valine - adverse effects Valine - analogs & derivatives Valine - therapeutic use |
| title | Intensification of Peritoneal Dialysis Improves Valacyclovir Neurotoxicity |
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