Hemodiafiltration in Pentobarbital Poisoning

Hemodiafiltration in Pentobarbital Poisoning

We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the...

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Veröffentlicht in:Renal failure 1996-01, Vol.18 (2), p.299-303
Hauptverfasser: Bironneau, Evelyne, Garrec, Françoise, Kergueris, Marie France, Testa, Angelo, Nicolas, Françoise
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Adult
Biological and medical sciences
Drug intoxications. Doping
Fatal Outcome
Hemodiafiltration - instrumentation
Hemodiafiltration - methods
Humans
Hypnotics and Sedatives - poisoning
Male
Medical sciences
Pentobarbital - poisoning
Pharmacology. Drug treatments
Poisoning - therapy
Suicide
Time Factors
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Beschreibung
Zusammenfassung:We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the end of treatment. This report suggests that CVVHD can be effective in the treatment of massive pentobarbital intoxication.
ISSN:0886-022X
1525-6049
DOI:10.3109/08860229609052800