Serotonergt syndrom - en fallbeskrivning

A patient developed severe myoclonus when treated with a combination of clomipramine, tryptophan, and electroconvulsive therapy. During the past 10 years there have been several reports on the "serotonin syndrome" as a complication when patients are treated with especially MAOIs or 5-HT-re...

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Veröffentlicht in:Nordic journal of psychiatry 1992, Vol.46 (2), p.117-119
1. Verfasser: Persson, Roy
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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Zusammenfassung:A patient developed severe myoclonus when treated with a combination of clomipramine, tryptophan, and electroconvulsive therapy. During the past 10 years there have been several reports on the "serotonin syndrome" as a complication when patients are treated with especially MAOIs or 5-HT-reuptake inhibitors in combination with tryptophan. It is important to recognize the syndrome, as we get more potent and specific 5-HT-reuptake inhibitors and especially as fatal outcome has been reported. The treatment seems to be immediate discontinuation of the medication.
ISSN:0803-9488
1502-4725
DOI:10.3109/08039489209103312