Analysis of Nifedipine and Related Compounds in Soft Geletin Capsules by Liquid Chromatography

Abstract A simple, sensitive, highly specific, stability-indicating, reversed-phase HPLC method for the quantitation of nifedipine and its related compounds such as nitrophenyl pyridine, nitrosophenyl pyridine analogs with average recoveries greater than 100% were obtained using a mobile phase metha...

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Veröffentlicht in:	Drug development and industrial pharmacy 1991, Vol.17 (16), p.2239-2244
Hauptverfasser:	Bammi, R. K., Nayak, V. G., Bhate, V. R., Dhumal, S. N., Purandare, S. M., Dikshit, P. M., Gaitonde, C. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biological and medical sciences General pharmacology Medical sciences Pharmacology. Drug treatments
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Zusammenfassung:	Abstract A simple, sensitive, highly specific, stability-indicating, reversed-phase HPLC method for the quantitation of nifedipine and its related compounds such as nitrophenyl pyridine, nitrosophenyl pyridine analogs with average recoveries greater than 100% were obtained using a mobile phase methanol-water (55:45, v/v) at 265 nm.
ISSN:	0363-9045 1520-5762
DOI:	10.3109/03639049109048073