The Influence of Granulation Process and Surfactants on the Biopharmaceutical Properties of Phenylbutazone Tablets
Abstract The influence of granulation process on the biopharmaceutical properties of experimental tablets has been studied, using phenyl butazone as a model substance. Four wet granulation procedures were compared. Moreover, in order to assess the influence of some surfactants, four different formul...
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Veröffentlicht in: | Drug development and industrial pharmacy 1988, Vol.14 (12), p.1713-1734 |
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Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Abstract
The influence of granulation process on the biopharmaceutical properties of experimental tablets has been studied, using phenyl butazone as a model substance. Four wet granulation procedures were compared. Moreover, in order to assess the influence of some surfactants, four different formulations were investigated |
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ISSN: | 0363-9045 1520-5762 |
DOI: | 10.3109/03639048809151983 |