Treatment of Cystinuria with Alpha-Mercaptopropionylglycine

Treatment of Cystinuria with Alpha-Mercaptopropionylglycine

Four cystinuric patients (3 females and 1 male) with recurrent L-cystine stone formation were treated with α-mercaptopropionyl glycine (MPG). In one patient the treatment was stopped because of a rash developing after one week of treatment. In the other 3 patients MPG was found to be as effective as...

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Veröffentlicht in:Scandinavian journal of urology and nephrology 1980, Vol.14 (2), p.189-192
Hauptverfasser: Johansen, K., Gammelgård, P. A., Schönau Jørgensen, F.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Amino Acids, Sulfur - therapeutic use
Cystine - metabolism
Cystinuria - complications
Cystinuria - drug therapy
Female
Humans
Male
Recurrence
Tiopronin - adverse effects
Tiopronin - therapeutic use
Urinary Calculi - etiology
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Beschreibung
Zusammenfassung:Four cystinuric patients (3 females and 1 male) with recurrent L-cystine stone formation were treated with α-mercaptopropionyl glycine (MPG). In one patient the treatment was stopped because of a rash developing after one week of treatment. In the other 3 patients MPG was found to be as effective as penicillamine in lowering the urinary cystine excretion to safe levels. No serious side effects of the drug were recorded.
ISSN:0036-5599
1651-2065
DOI:10.3109/00365598009179559