Gonadal dysgemiinoma-seminoma associated with severe hypercalcemia

Gonadal dysgemiinoma-seminoma associated with severe hypercalcemia

A case is reported, of a 25-year-old phenotypic female, karyotypic male patient with metastatic gonadal dysgerminoma-seminoma and severe hypercalcemic paraneoplastic syndrome. Patient manifested normal female external genitalia, vagina, uterus, and fallopian tubes but with 46 XY karyotype. Adnexal g...

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Veröffentlicht in:Acta obstetricia et gynecologica Scandinavica 1993, Vol.72 (1), p.57-59
Hauptverfasser: Bakri, Younes N., Akhtar, M.
Format: Artikel
Sprache:eng
Schlagworte:
dysgerminoma
gonadoblastoma
gonads
hypercalcemia
karyotype
seminoma
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Zusammenfassung:A case is reported, of a 25-year-old phenotypic female, karyotypic male patient with metastatic gonadal dysgerminoma-seminoma and severe hypercalcemic paraneoplastic syndrome. Patient manifested normal female external genitalia, vagina, uterus, and fallopian tubes but with 46 XY karyotype. Adnexal gonads were calcified. External beam radiation therapy resolved the hypercalcemic state. Exploratory laparotomy after irradiation revealed gonado-blastoma originating from dysgenetic gonads.
ISSN:0001-6349
1600-0412
DOI:10.3109/00016349309013353