Behavioral effect of soymorphin-5-amide in rats

Behavioral effects of YPFVV-NH 2 (an analogue of soymorphin-5, an exorphin derived from a soy protein) in rats were investigated for the first time. Rats of different sex and age were tested. It was shown that the stimulation of locomotion in adult rats (males) was the main effect of the peptide inj...

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Veröffentlicht in:	Moscow University biological sciences bulletin 2014-09, Vol.69 (3), p.103-107
Hauptverfasser:	Chesnokova, E. A., Saricheva, N. J., Dubynin, V. A., Kamenskij, A. A., Kalikhevich, V. N., Adermasova, Z. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Cell Biology Life Sciences Physiology Plant Sciences Zoology
Online-Zugang:	Volltext
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Zusammenfassung:	Behavioral effects of YPFVV-NH 2 (an analogue of soymorphin-5, an exorphin derived from a soy protein) in rats were investigated for the first time. Rats of different sex and age were tested. It was shown that the stimulation of locomotion in adult rats (males) was the main effect of the peptide injection. In juvenile rats, in turn, the main effect of YPFVV-NH 2 was related to anxiety. The anxiolytic effect superseded the anxiogenic effect during puberty. Finally, the manifestation of the peptide effects depended on animals’ stress level.
ISSN:	0096-3925 1934-791X
DOI:	10.3103/S0096392514030055