Nitric oxide plays a role in the protective effects of short-term adaptation to hypoxia on the stress-induced disorders in rats of the Krushinsky-Molodkina strain
The NO-synthase inhibitor L-NNA (2.5 mg/100 g) abolished the protective effects of short-term adaptation to hypoxia (1 h, 5000 m above sea level) on the development of stress-induced disorders on the model of acoustic stress in the Krushinskii-Molodkina rats genetically predisposed to audiogenic sei...
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| Veröffentlicht in: | Moscow University biological sciences bulletin 2010, Vol.65 (1), p.1-4 |
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| container_title | Moscow University biological sciences bulletin |
| container_volume | 65 |
| creator | Kuzenkov, V. S Reutov, V. P Krushinsky, A. L Koshelev, V. B Sorokina, E. G Baider, L. M Kuropteva, Z. V Komissarova, L. Kh |
| description | The NO-synthase inhibitor L-NNA (2.5 mg/100 g) abolished the protective effects of short-term adaptation to hypoxia (1 h, 5000 m above sea level) on the development of stress-induced disorders on the model of acoustic stress in the Krushinskii-Molodkina rats genetically predisposed to audiogenic seizures. Using the electronic spine resonance method (ESR) we also demonstrated an increase in NO production during short-term hypoxia in the blood and spleen. The results suggest that NO plays a positive role in protective effects of short-term adaptation to hypoxia. |
| doi_str_mv | 10.3103/S0096392510010013 |
| format | Article |
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| ispartof | Moscow University biological sciences bulletin, 2010, Vol.65 (1), p.1-4 |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Biochemistry Biomedical and Life Sciences Cell Biology Life Sciences Plant Sciences Zoology |
| title | Nitric oxide plays a role in the protective effects of short-term adaptation to hypoxia on the stress-induced disorders in rats of the Krushinsky-Molodkina strain |
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