A case of hepatic inflammatory pseudo-tumor of the liver mimicking a metastatic tumor of colon and/or bile duct cancer

The patient was a 71-year-old-male, who had history of extrahepatic bile duct resection for bile duct cancer. Abdominal CT revealed two low density areas in S5 and S6. EOB-MRI revealed multiple masses in both lobes of liver, which were a hypointensity in the hepatobiliary phase. Imaging modalities suggested that these masses were metastatic liver tumor. However, we could not diagnose the primary lesion of this liver tumor. We performed percutaneous needle biopsy of the liver tumor to clarify the primary lesion.Histopathogical examination for tumor biopsy specimen confirmed no evidence of malignant change, and revealed remarkable fibrosis with scattered chronic inflammatory cell infiltration. Moreover, histological findings of the liver around the tumor lesion showed inflammatory cell infiltration, fibrosis and ductural proliferation in the portal area that reflect chronic cholangitis. Hepatic inflammatory pseudo-tumor as a sequel of chronic cholangitis is a rare condition.