Pathophysiological resarch of autoimmune liver disease: Human cytokine genes expression in SCID mice liver reconstituted with mononuclear cells of patients

Pathophysiological resarch of autoimmune liver disease: Human cytokine genes expression in SCID mice liver reconstituted with mononuclear cells of patients

Peripheral blood mononuclear cells (PBMC) from patients with autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and healthy individuals were recostituted into sever combined immunodeficient (SCID) mice to investigate human cytokine genes expression in the mice liver. Production of human imm...

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Veröffentlicht in:Kanzo 1994/07/25, Vol.35(7), pp.518-526
Hauptverfasser: KIMURA, Yasuhiko, Morshed, Syed Ahmed, NISHIOKA, Mikio
Format: Artikel
Sprache:jpn
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Zusammenfassung:Peripheral blood mononuclear cells (PBMC) from patients with autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and healthy individuals were recostituted into sever combined immunodeficient (SCID) mice to investigate human cytokine genes expression in the mice liver. Production of human immunoglobulins (Ig) in SCID mice reconstituted with AIH-PBMC was significantly (p
ISSN:0451-4203
1881-3593
DOI:10.2957/kanzo.35.518