Hepatic angiosarcoma and hepatocellular carcinoma in a single patient with histological characteristics similar to idiopathic portal hypertension

A 59-year-old man without any history of thorotrast injection, inhalation of vinyl chloride or any other specific causes, visited our hospital because of further examination of giant tumors of the liver detected by abdominal ultrasonography (US). On admission, his laboratory data showed thrombocytopenia and a prolonged prothrombin time. Endoscopic examination revealed esophageal varices and cardial varices. CT imaging and US demonstrated two giant tumors of the liver. He died of hepatic failure and respiratory failure in three months after admission. The autopsy findings disclosed hepatic angiosarcoma and hepatocellular carcinoma with fibrosis similar to idiopathic portal hypertension and metastases of angiosarcoma in both lungs and bone marrow.