Pathological study 0f the toxic effect of paracetamol on reproductive organs in white mice
In present study use 40 mice (20 male and 20 females) divided into 4 groups, each grouphas 10 mice.The first group gave distal water considered as control group. The second (lowdose group) gave 28.5 mg / kg B.W. paracetamol. The third group(intermediate dose group)gave 57 mg / kg B.W. paracetamol an...
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Veröffentlicht in: | Al-Qadisiyah Journal of Veterinary Medicine Sciences 2010-12, Vol.9 (3), p.1 |
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | In present study use 40 mice (20 male and 20 females) divided into 4 groups, each grouphas 10 mice.The first group gave distal water considered as control group. The second (lowdose group) gave 28.5 mg / kg B.W. paracetamol. The third group(intermediate dose group)gave 57 mg / kg B.W. paracetamol and fourth group(high dose group) gave 114 mg / kg B.W.paracetamol daily for 6 month. Also there was another group considerd as peracute dosegroup(supra toxic) contains from 2 males and 2 females gave 342 mg / kg B.W. (for 2weeks).The toxic and supra toxic dose 0f paracetamol caused macroscopic and microscopicchanges in male and female reproductive organs in white mice |
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ISSN: | 1818-5746 2313-4429 |
DOI: | 10.29079/vol9iss3art111 |