Pathological diagnoses and adenosine deaminase levels in patients undergoing pericardial window operation for large pericardial effusions
Background: It might be challenging to determine the etiology of pericardial effusions as studies have usually focused on pericardial effusions in patients suspected to have specific underlying clinical conditions. We aimed to evaluate adenosine deaminase (ADA) levels in pericardial fluid samples of...
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Veröffentlicht in: | Current thoracic surgery 2023, Vol.8 (3), p.143 |
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Sprache: | eng |
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Zusammenfassung: | Background: It might be challenging to determine the etiology of pericardial effusions as studies
have usually focused on pericardial effusions in patients suspected to have specific underlying clinical
conditions. We aimed to evaluate adenosine deaminase (ADA) levels in pericardial fluid samples
of patients with large pericardial effusions in whom pericardial window surgeries with biopsy and
pathological examinations were carried out.
Materials and Methods: Pericardial fluid ADA levels of 149 consecutive patients having large pericardial
effusions were evaluated. Pericardial effusion was detected by transthoracic echocardiography, ADA
levels were measured from the fluid taken during pericardial windowing procedure, and pathological
examination of the tissue samples were performed.
Results: The median age of selected patients participating in the study was 58.43 ± 14.47 years. All the
pericardial fluid samples were found to be exudative and 116 (77.9 %) of the cases had also concomitant
pleural effusions. The median ADA level of the cases was calculated to be 19.57 U/L (9.47-38.70), well
below the cut-off value (40 U/L). The mean ADA levels value was 9.21 U/L (7.70-9.91) in the nonspecific
inflammations group and 38.35 U/L (23.92-48.67) in the lung malignancy group (p |
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ISSN: | 2548-0316 2548-0316 |
DOI: | 10.26663/cts.2023.0025 |