THE ROLE OF GASTRIC LOCALIZATION AND THE GASTRITIS SCORE OF HELICOBACTER PYLORI IN THE DEVELOPMENT OF EROSIVE ESOPHAGITIS

Objective: The interactions between Helicobacter pylori (Hp) and gastroesophageal reflux disease (GERD) are a complex issue. The aim of this study was to investigate the correlation between Hp infection and the gastric localization of Hp and reflux esophagitis (RE) in adult patients. Material and Me...

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Veröffentlicht in:İstanbul Tıp Fakültesi Dergisi 2020-06, Vol.83 (3), p.221-226
Hauptverfasser: YALAKİ, Serkan, PULAT, Hüseyin
Format: Artikel
Sprache:eng
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Zusammenfassung:Objective: The interactions between Helicobacter pylori (Hp) and gastroesophageal reflux disease (GERD) are a complex issue. The aim of this study was to investigate the correlation between Hp infection and the gastric localization of Hp and reflux esophagitis (RE) in adult patients. Material and Method: Two hundred thirty-nine patients with RE were compared with 229 age and sex matched participants in a control group. Biopsy specimens obtained from the gastric antrum and corpus were histologically evaluated. Results: The prevalence of Hp infection was significantly lower in the patients with RE than in the control group (Odds ratio 1.56, 95% CI 1.08-2.27; p=0.02, p
ISSN:1305-6433
1305-6441
1305-6441
DOI:10.26650/IUITFD.2019.0085