Patterns of Failure after Photodynamic Therapy of Newly Diagnosed Glioblastoma Patients

The effect of photodynamic therapy (PDT) on newly diagnosed glioblastoma patients was retrospectively evaluated. PDT significantly prevented the tumor progression from the lateral wall of the resection cavity, but did not prevent recurrence from the bottom of the cavity. The incidence of adverse events after craniotomy was similar regardless of PDT. PDT was safe, and prevented recurrence from the lateral wall of the resection cavity, resulted in prolonged maintenance of PS, and improved survival of patients.