Exploring the Pharmacological Potential of Fisetin: A Comprehensive Review

Fisetin, a hydrophobic polyphenolic molecule, is a naturally occurring flavonoid commonly found in fruits and vegetables. The popularity of fisetin comes mainly from its many different medical uses. Known for its antioxidant and anti-inflammatory effects, fisetin is likely to be useful in the treatment of just about any inflammatory disease. Its ability to induce apoptosis (programmed cell death) and encourage tumor regression is another key reason fisetin’s anti-cancer effects are so striking Furthermore, fisetin has excellent antibacterial capabilities, its spectrum encompassing all kinds of bugs: bacteria, viruses of many types and fungi. Notably, fisetin also exhibits neuroprotective and cardioprotective attributes, making it a compound of significant interest for multiple health-related applications. It also shows promise in controlling diabetes and shielding the skin from UV ray damage. Preclinical research has suggested the effectiveness of fisetin, but further investigation, including clinical trials, is necessary to confirm its safety and effectiveness in humans. Furthermore, this review would benefit future studies on fisetin’s therapeutic potential.