Exploring the Role of Phytochemicals in Arthritic Disorders: A Review

Rheumatoid arthritis (RA) is a prevalent inflammatory condition exemplified by a prolonged course and diverse levels of complexity in symptoms involving joints, extra-articular organs and systemic manifestations, impacting a substantial number of people worldwide. The current treatment regimen of RA involves various synthetic drugs which cause severe side effects and occasionally infections also having high cost and impaired life quality. Plants and herbs contain abundant phytochemicals, which have demonstrated effectiveness in preventing, treating, or alleviating a range of health issues. Phytochemicals due to their low cost, safety and effectiveness in RA treatment and better patient acceptability are used as an alternative therapy. Currently, varied phytochemicals are isolated and evaluated for anti-arthritic drugs as they possess diverse chemical structures and specific biological actions. Phytochemicals are tested as a novel curative approach for arthritis management. In the present review, our intention is to present the role of different phytochemicals in reducing the progression of RA. We also aim to present a mechanism-based reduction of arthritic symptoms