Relationship between Information of Phase in a Parent and Required Head of Animals for Linkage Analysis between DNA Polymorphic Loci Including Three Markers or More in Pigs

Two different cases were compared in their efficiency for the detection of linkage between DNA polymorphic loci in pigs using computer simulation. In the first case, the presence of DNA polymorphism of the sire's parents were left unchecked, while in the second case, linkage analysis was performed after checking DNA polymorphism of the sire's parents in order to obtain information of the phase of the sire. In the simulation experiments, the sire was assumed to be doubly heterozygous and the linkage phase of the sire was assumed to be unknown. In the case where recombination rate was 0.05 or less, the first case was more efficient for detecting linkage between markers than the second case, while the second case was more efficient than the first case when the recombination rate was more than 0.05.