Hepatoprotective activity of different leaves extracts of Convolvulus pluricaulis against CCl4 induced liver damage

The study was designed to assess the hepatoprotective activity of various extracts (Pet. ether, chloroform, ethyl acetate, ethanol & aqueous) of leaves of Convolvulus pluricaulis in carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Amongst all the extracts, ethyl acetate extract (200 a...

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Veröffentlicht in:International journal of pharmaceutical sciences and drug research 2022-07, p.476-484
Hauptverfasser: Tamboli, Ashpak M., Wadkar, Kiran A.
Format: Artikel
Sprache:eng
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Zusammenfassung:The study was designed to assess the hepatoprotective activity of various extracts (Pet. ether, chloroform, ethyl acetate, ethanol & aqueous) of leaves of Convolvulus pluricaulis in carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Amongst all the extracts, ethyl acetate extract (200 and 400 mg/kg) significantly normalized the CCl4-elevated levels of serum SGPT, SGOT, ALP and TB and GSH, CAT and considerably reduced the serum levels of MDA compared to CCl4 group (**p
ISSN:0975-248X
0975-248X
DOI:10.25004/IJPSDR.2022.140414