Self-assembly of Amphiphilic Peptide in Phospholipid Membrane

Self-assembly of Amphiphilic Peptide in Phospholipid Membrane

An amphiphilic molecule Lipid-(RADA)2 consisting of a repeating RADA peptide sequence and alkyl chains appending a fluorescent nitrobenzoxadiazole (NBD) dye, was synthesized. In a fluorescence microscopic observation, localization of an aggregate containing Lipid-(RADA)2 at a bilayer membrane formed...

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Veröffentlicht in:Journal of Photopolymer Science and Technology 2021/06/11, Vol.34(2), pp.155-159
Hauptverfasser: Kawakita, Anju, Uchida, Noriyuki, Ryu, Yunosuke, Muraoka, Takahiro
Format: Artikel
Sprache:eng
Schlagworte:
Fluorescence microscopy
Peptide
Phospholipid
Self-assembly
Vesicle
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Zusammenfassung:An amphiphilic molecule Lipid-(RADA)2 consisting of a repeating RADA peptide sequence and alkyl chains appending a fluorescent nitrobenzoxadiazole (NBD) dye, was synthesized. In a fluorescence microscopic observation, localization of an aggregate containing Lipid-(RADA)2 at a bilayer membrane formed with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) was observed.
ISSN:0914-9244
1349-6336
DOI:10.2494/photopolymer.34.155