T4 Adenocarcinoma of the Lung Curatively Resected after MVP Neoadjuvant Chemotherapy with Recombinant Human Granulocyte Colony-Stimulating Factor

A 65-year-old male was diagnosed as having adenocarcinoma of the lung extensivelyinfiltrating the mediastinum at exploratory thoracotomy. After five cycles of neoadjuvant chemotherapy (MVP; MMC+VDS+CDDP) with recombinant humangranulocyte colony-stimulating factor (rhG-CSF), complete response was achieved.Subsequently, left upper lobectomy was able to be performed. Postoperative histological studies showed no malignant cells in all sections examined. We conclude that neoadjuvant chemotherapy with rhG-CSF enables more rapid delivery of full-dose cycles of anticancer agents, and that dose-intensitive chemotherapy is suitable for advanced non-small cell lung cancer.