Evaluation of Therapeutic Effect on Lung Cancer-Comparison of Actual Survival to Survival Predicted by Actual Tumor Volume Doubling Time and Tumor Diameter on First Observation

The predicted survival time of 56 patients with lung cancer was calculated using Geddes' nomogram for tumor size on first observation (Do) and tumor doubling time (DT) calculated according to Schwarz's formula. The patients were grouped by histologic types into squamous cell carcinoma (22 cases), adenocarcinoma (23), small cell carcinoma (6) and large cell carcinoma (5). They were further divided by the mode of treatment: resection (28 cases), radiation (14), chemotherapy (12) and no treatment (2). The predicted survival time (PST) correlated favorably with the actual survival time (AST). The correlation between PST (x) and AST (y) by least squares regression was y=2.33+0.82x (r=0.80, p