Vitamin D Deficiency in Patients Receiving Antidepressant Medications

Тhis study aimed at exploring vitamin D levels in treated depressive patients in comparison to healthy individuals. The cross-sectional study included 20 ambulatory and inpatients with depressive episodes taking antidepressants and 30 healthy individuals. The serum concentration of 25(OH)D from collected blood samples was determined using biochemical analyzers. Serum 25(OH)D levels (ng/mL) in patients were significantly lower (the mean 13.1, standard deviation 7.3, median 11.4, minimal 3.8, maximal 35.9) then in control subjects (19.4, 9.1, 15.8, 7.6, 43.6) (p=0.004). Additional targeted research is needed because some lifestyle and dietary habits which are known to influence vitamin D status may confound observed effects.