“Prolonged” migraine aura: New information on underlying mechanisms

The aim of this study is to identify the pathophysiology of “prolonged” migraine aura not clearly understood. We studied cortical cerebral microcirculation by Near Infrared Spectroscopy system (NIRS) and cerebral macrocirculation by transcranial Doppler (TCD) in 8 subjects (3 M and 5 F, age range 21...

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Veröffentlicht in:Translational neuroscience 2011-06, Vol.2 (2), p.101-105
Hauptverfasser: Viola, Stefano, Viola, Paolo, Litterio, Pasqualino, Buongarzone, Maria Pia, Fiorelli, Luisa
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Sprache:eng
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Zusammenfassung:The aim of this study is to identify the pathophysiology of “prolonged” migraine aura not clearly understood. We studied cortical cerebral microcirculation by Near Infrared Spectroscopy system (NIRS) and cerebral macrocirculation by transcranial Doppler (TCD) in 8 subjects (3 M and 5 F, age range 21–41 years) during spontaneous “prolonged” migraine aura in according to ICHD-II criteria 2004 (code 1.6.2.) up to 24 hours after the end of aura and compared the results with the headache-free periods. During aura NIRS showed a significant decrease of the Arterial Pulse Wave of Cerebral Microcirculation (APWCM) amplitude (−33 % ± 5.7), p
ISSN:2081-3856
2081-6936
DOI:10.2478/s13380-011-0014-5