One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides to N-alkyl-2-(2-hydroxyphenyl)-2-imino-acetamides

One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides to N-alkyl-2-(2-hydroxyphenyl)-2-imino-acetamides

One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides is reported. N-alkyl-2-(2-hydroxyphenyl)-2-iminoacetamide derivatives are generated presumably via the preliminary formation of N, N′-disubstituted benzo[b]furan-2,3-diamines and subsequ...

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Veröffentlicht in:Central European journal of chemistry 2010-08, Vol.8 (4), p.899-905
Hauptverfasser: Ghandi, Mehdi, Asgari, Parham, Taheri, Abuzar, Abbasi, Alireza
Format: Artikel
Sprache:eng
Schlagworte:
2-Hydroxybenzaldehyde derivatives
Biochemistry
Biological and Medical Physics
Biophysics
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Geochemistry
Research Article
Three-component
Ugi reaction
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Zusammenfassung:One-pot, three-component condensation of 2-hydroxybenzaldehyde derivatives, primary amines with alkyl isocyanides is reported. N-alkyl-2-(2-hydroxyphenyl)-2-iminoacetamide derivatives are generated presumably via the preliminary formation of N, N′-disubstituted benzo[b]furan-2,3-diamines and subsequent oxidation with molecular oxygen.
ISSN:1895-1066
2391-5420
1644-3624
2391-5420
DOI:10.2478/s11532-010-0054-7