Malignant Transformation of Laryngeal Papilloma: A Case Report

A case of laryngeal papilloma with malignant change in a 84-year-old female was reported. This patient has suffered from hoarseness since October 1988. She visited a neighboring ENT clinic and was urged to surgical treatment. However, she waited almost two years without undergoing any treatment. In October 1990, she visited us because of severe difficulty in respiration. A laryngoendoscopy revealed a papillomatous tumor occupying the laryngeal cavity. Successively, she underwent laryngomicrosurgery using the CO2 laser technique. A histopathological study revealed that the tumor was a papilloma with a highly dysplastic change. Unexpectedly, a recurrence was endoscopically found at the right vocal fold in July 1991. Laryngomicrosurgery with a CO2 laser was immediately performed again. Our histopathological division reported that a squamous cell carcinoma was found in part of the specimen.