Translating Lifestyle Intervention to Practice in Obese Patients With Type 2 Diabetes

Translating Lifestyle Intervention to Practice in Obese Patients With Type 2 Diabetes Improving Control with Activity and Nutrition (ICAN) study Anne M. Wolf , MS 1 , Mark R. Conaway , PHD 1 , Jayne Q. Crowther , RN 1 , Kristen Y. Hazen , MS 1 , Jerry L.Nadler , MD 2 , Beverly Oneida , MS 3 and Vikt...

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Veröffentlicht in:Diabetes care 2004-07, Vol.27 (7), p.1570-1576
Hauptverfasser: Wolf, Anne M., Conaway, Mark R., Crowther, Jayne Q., Hazen, Kristen Y., L.Nadler, Jerry, Oneida, Beverly, Bovbjerg, Viktor E.
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Sprache:eng
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Zusammenfassung:Translating Lifestyle Intervention to Practice in Obese Patients With Type 2 Diabetes Improving Control with Activity and Nutrition (ICAN) study Anne M. Wolf , MS 1 , Mark R. Conaway , PHD 1 , Jayne Q. Crowther , RN 1 , Kristen Y. Hazen , MS 1 , Jerry L.Nadler , MD 2 , Beverly Oneida , MS 3 and Viktor E. Bovbjerg , PHD 1 1 Department of Health Evaluation Sciences, University of Virginia School of Medicine, Charlottesville, Virginia 2 Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Virginia School of Medicine, Charlottesville, Virginia 3 Southern Health Services, Richmond, Virginia Address correspondence and reprint requests to Anne Wolf, Department of Health Evaluation Sciences, Box 800717, Charlottesville, VA 22908-0717. E-mail: amw6n{at}virginia.edu Abstract OBJECTIVE —To assess the efficacy of a lifestyle intervention program that can be readily translated into clinical practice for obese patients with type 2 diabetes. RESEARCH DESIGN AND METHODS —The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI ≥27 kg/m 2 ). Participants were randomized to lifestyle case management or usual care. Case management entailed individual and group education, support, and referral by registered dietitians; intervention cost was $350 per person. Individuals treated with usual care received educational material. Both groups received ongoing primary care. Outcomes were difference between groups for change in weight (kilograms), waist circumference (centimeters), HbA 1c , fasting lipid levels, use of prescription medications, and health-related quality of life. RESULTS —Case management resulted in greater weight loss ( P < 0.001), reduced waist circumference ( P < 0.001), reduced HbA 1c level ( P = 0.02), less use of prescription medications ( P = 0.03), and improved health-related quality of life ( P < 0.001) compared with usual care. The 12-month group difference in weight loss and waist circumference was 3.0 kg (95% CI −5.4 to −0.6) and −4.2 cm (−6.8 to −1.6). HbA 1c differences were greatest at 4 months (−0.59%, P = 0.006) but not significant by 12 months (−0.19%, P = 0.45). Participants in the case management group lowered their use of medications, primarily diabetes medications, by 0.8 medications per day more than participants treated with usual care ( P = 0.03). In seven of nine quality-of-life domains, the case management group improved compared with usu
ISSN:0149-5992
1935-5548
DOI:10.2337/diacare.27.7.1570