Glycemic Control From 1988 to 2000 Among U.S. Adults Diagnosed With Type 2 Diabetes

Glycemic Control From 1988 to 2000 Among U.S. Adults Diagnosed With Type 2 Diabetes A preliminary report Carol E. Koro , PHD 1 2 , Steven J. Bowlin , DO, PHD 1 , Nancy Bourgeois , BS 1 and Donald O. Fedder , DPH 2 1 GlaxoSmithKline, Upper Providence, Pennsylvania 2 University of Maryland, Baltimore, Maryland Address correspondence and reprint requests to Carol E. Koro, 1250 South Collegeville Rd., UP4305, Collegeville, PA 19426-0989. E-mail: ckoro001{at}umaryland.edu Abstract OBJECTIVE —To describe the changes in demographics, antidiabetic treatment, and glycemic control among the prevalent U.S. adult diagnosed type 2 diabetes population between the National Health and Nutrition Examination Survey (NHANES) III (1988–1994) and the initial release of NHANES 1999–2000. RESEARCH DESIGN AND METHODS —The study population was derived from NHANES III ( n = 1,215) and NHANES 1999–2000 ( n = 372) subjects who reported a diagnosis of type 2 diabetes with available data on diabetes medication and HbA 1c . Four therapeutic regimens were defined: diet only, insulin only, oral antidiabetic drugs (OADs) only, or OADs plus insulin. Multiple logistic regression was used to examine changes in antidiabetic regimens and glycemic control rates over time, adjusted for demographic and clinical risk factors. The outcome measure for glycemic control was HbA 1c . Glycemic control rates were defined as the proportion of type 2 diabetic patients with HbA 1c level