Elevated ANGPTL5 Level in the Circulation of Obese and Type 2 Diabetic People

Angiopoetin like protein family is composed of eight members that are involved in regulating various metabolic processes. ANGPTL5 is one of the members of this family that is mainly expressed in the heart and was showed to stimulate the expansion of human cord blood hematopoietic stem cell ex-vivo....

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2018-07, Vol.67 (Supplement_1)
Hauptverfasser: ABU-FARHA, MOHAMED, ALHASAWI, NOUF, QADDOUMI, MOHAMMAD, ALMULLA, FAHD, TUOMILEHTO, JAAKKO, ALANBAEI, MUATH, ABUBAKER, JEHAD
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Sprache:eng
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Zusammenfassung:Angiopoetin like protein family is composed of eight members that are involved in regulating various metabolic processes. ANGPTL5 is one of the members of this family that is mainly expressed in the heart and was showed to stimulate the expansion of human cord blood hematopoietic stem cell ex-vivo. This study was designed to investigate the expression level of this protein in the plasma of obese and diabetic people. Methods: A total of 204 people were enrolled in this study including 109 nondiabetic and 95 type 2 diabetics. The nondiabetic people included 70 non-obese (BMI
ISSN:0012-1797
1939-327X
DOI:10.2337/db18-301-LB