Endobarrier (EB) in Type 2 Diabetes/Prediabetes with Obstructive Sleep Apnea Study—Preliminary Results
Aims: To assess the extent to which patients with type 2 diabetes or prediabetes, obesity (BMI 30-45kg/m²) and moderate OSA requiring continuous positive airway pressure ventilation (CPAP) are able to discontinue CPAP following EB-related weight loss (ISRCTN33788132). Methods: We assessed Apnoea Hyp...
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| Veröffentlicht in: | Diabetes (New York, N.Y.) N.Y.), 2018-07, Vol.67 (Supplement_1) |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Zusammenfassung: | Aims: To assess the extent to which patients with type 2 diabetes or prediabetes, obesity (BMI 30-45kg/m²) and moderate OSA requiring continuous positive airway pressure ventilation (CPAP) are able to discontinue CPAP following EB-related weight loss (ISRCTN33788132).
Methods: We assessed Apnoea Hypopnoea Index (AHI), weight and HbA1c before and following EB. The full study involves 18 patients receiving EB for up to 1 year with 1 year follow-up.
Results: We report here the 1st 11 patients {9/11 (82%) female, 9/11 (82%) type 2 diabetes, 2/11 (18%) prediabetes, mean ± SD age 52.6 ± 9.7 years} to reach at least 3 months EB treatment. In 3 months, weight fell by 6.9 ± 3.3kg from 103.7 ± 14.8 to 96.8 ± 14.8kg (p |
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| ISSN: | 0012-1797 1939-327X |
| DOI: | 10.2337/db18-2071-P |