Basic study of the Effects of Minocycline HCl on Periodontally-involved Root Surfaces
The acid conditioning effects of minocycline on the root surface with mechanical root cleaning were investigated in this study. Root surface specimens were randomly assigned to scaling group (control), polishing group (polish), superficial debridement group (SL) and deep debridement group (DL) with...
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| Veröffentlicht in: | Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 1999/09/28, Vol.41(3), pp.338-345 |
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| container_title | Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) |
| container_volume | 41 |
| creator | Yoshino, Takashi Suzuki, Fumihiko Sekino, Satoshi Tashiro, Toshio Aiba, Toshifumi Minabe, Masato Okamoto, Hiroshi |
| description | The acid conditioning effects of minocycline on the root surface with mechanical root cleaning were investigated in this study. Root surface specimens were randomly assigned to scaling group (control), polishing group (polish), superficial debridement group (SL) and deep debridement group (DL) with minocycline solution (10mg/ml). The antimicrobial activities of minocycline solution (10mg/ml, 10min) against P. gingivalis, by moniforing penetration rate and attachment rate were evaluated. The results showed that all groups possessed antimicrobial activity against P. gingivalis on days 0 and 7 after root conditioning with minocycline solution (10mg/ml, 10 min). Especially, DL group exhibited significantly higher antimicrobial activity (Day 0: average 94.8 unit [p |
| doi_str_mv | 10.2329/perio.41.338 |
| format | Article |
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Root surface specimens were randomly assigned to scaling group (control), polishing group (polish), superficial debridement group (SL) and deep debridement group (DL) with minocycline solution (10mg/ml). The antimicrobial activities of minocycline solution (10mg/ml, 10min) against P. gingivalis, by moniforing penetration rate and attachment rate were evaluated. The results showed that all groups possessed antimicrobial activity against P. gingivalis on days 0 and 7 after root conditioning with minocycline solution (10mg/ml, 10 min). Especially, DL group exhibited significantly higher antimicrobial activity (Day 0: average 94.8 unit [p<0.01], Day 7: average 54.1 unit [p<0.05]). The penetration rate to root surfaces were significantly higher in the DL group (42.7. μm) and in the SL group (21.5. μm) (p<0.01). In the attachment rate, the SL 92.8% and DL groups 97.2% were significantly higher than other groups (p<0.01). These results suggest that minocycline root conditioning will be expected on the cementum surfaces. J. Jpn. Soc. Periodontol., 41: 339-346, 1999.</description><identifier>ISSN: 0385-0110</identifier><identifier>EISSN: 1880-408X</identifier><identifier>DOI: 10.2329/perio.41.338</identifier><language>jpn</language><publisher>JAPANESE SOCIETY OF PERIODONTOLOGY</publisher><subject>antibial substantivity ; minocycline ; periodontally involved root surfaces ; root conditioning</subject><ispartof>Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 1999/09/28, Vol.41(3), pp.338-345</ispartof><rights>The Japanese Society of Periodontology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Yoshino, Takashi</creatorcontrib><creatorcontrib>Suzuki, Fumihiko</creatorcontrib><creatorcontrib>Sekino, Satoshi</creatorcontrib><creatorcontrib>Tashiro, Toshio</creatorcontrib><creatorcontrib>Aiba, Toshifumi</creatorcontrib><creatorcontrib>Minabe, Masato</creatorcontrib><creatorcontrib>Okamoto, Hiroshi</creatorcontrib><title>Basic study of the Effects of Minocycline HCl on Periodontally-involved Root Surfaces</title><title>Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)</title><addtitle>Nihon Shishubyo Gakkai Kaishi</addtitle><description>The acid conditioning effects of minocycline on the root surface with mechanical root cleaning were investigated in this study. Root surface specimens were randomly assigned to scaling group (control), polishing group (polish), superficial debridement group (SL) and deep debridement group (DL) with minocycline solution (10mg/ml). The antimicrobial activities of minocycline solution (10mg/ml, 10min) against P. gingivalis, by moniforing penetration rate and attachment rate were evaluated. The results showed that all groups possessed antimicrobial activity against P. gingivalis on days 0 and 7 after root conditioning with minocycline solution (10mg/ml, 10 min). Especially, DL group exhibited significantly higher antimicrobial activity (Day 0: average 94.8 unit [p<0.01], Day 7: average 54.1 unit [p<0.05]). The penetration rate to root surfaces were significantly higher in the DL group (42.7. μm) and in the SL group (21.5. μm) (p<0.01). In the attachment rate, the SL 92.8% and DL groups 97.2% were significantly higher than other groups (p<0.01). These results suggest that minocycline root conditioning will be expected on the cementum surfaces. J. Jpn. Soc. Periodontol., 41: 339-346, 1999.</description><subject>antibial substantivity</subject><subject>minocycline</subject><subject>periodontally involved root surfaces</subject><subject>root conditioning</subject><issn>0385-0110</issn><issn>1880-408X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNo9kN1OwzAMhSMEEtPYHQ-QB6DDqfuTXsI0GNIQCJjEXZWlDgsqzZR0k_r261a0C9uy_R1bOozdCpjGGBf3W_LWTRMxRZQXbCSkhCgB-X3JRoAyjUAIuGaTEOwaAGQeAxYjtnpUwWoe2l3VcWd4uyE-N4Z0G47tq22c7nRtG-KLWc1dw9-PfyrXtKquu8g2e1fvqeIfzrX8c-eN0hRu2JVRdaDJfx2z1dP8a7aIlm_PL7OHZaRFkcgIDZChPDEGMmkQshxjTA2kmYBY5lW8zkkYTQbyKoUc-7mOJaYIfWAlcczuhrvauxA8mXLr7Z_yXSmgPLpSnlwpE1H2rvT4fMB_Q6t-6Awr31pd0wCLIpMnwZB63XmvN8qX1OABVoxuJw</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>Yoshino, Takashi</creator><creator>Suzuki, Fumihiko</creator><creator>Sekino, Satoshi</creator><creator>Tashiro, Toshio</creator><creator>Aiba, Toshifumi</creator><creator>Minabe, Masato</creator><creator>Okamoto, Hiroshi</creator><general>JAPANESE SOCIETY OF PERIODONTOLOGY</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1999</creationdate><title>Basic study of the Effects of Minocycline HCl on Periodontally-involved Root Surfaces</title><author>Yoshino, Takashi ; Suzuki, Fumihiko ; Sekino, Satoshi ; Tashiro, Toshio ; Aiba, Toshifumi ; Minabe, Masato ; Okamoto, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1948-3f0efe74ff068f30673235f05610287d2b7e1fcef07d5073561c2835303533d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>1999</creationdate><topic>antibial substantivity</topic><topic>minocycline</topic><topic>periodontally involved root surfaces</topic><topic>root conditioning</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yoshino, Takashi</creatorcontrib><creatorcontrib>Suzuki, Fumihiko</creatorcontrib><creatorcontrib>Sekino, Satoshi</creatorcontrib><creatorcontrib>Tashiro, Toshio</creatorcontrib><creatorcontrib>Aiba, Toshifumi</creatorcontrib><creatorcontrib>Minabe, Masato</creatorcontrib><creatorcontrib>Okamoto, Hiroshi</creatorcontrib><collection>CrossRef</collection><jtitle>Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yoshino, Takashi</au><au>Suzuki, Fumihiko</au><au>Sekino, Satoshi</au><au>Tashiro, Toshio</au><au>Aiba, Toshifumi</au><au>Minabe, Masato</au><au>Okamoto, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Basic study of the Effects of Minocycline HCl on Periodontally-involved Root Surfaces</atitle><jtitle>Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)</jtitle><addtitle>Nihon Shishubyo Gakkai Kaishi</addtitle><date>1999</date><risdate>1999</risdate><volume>41</volume><issue>3</issue><spage>338</spage><epage>345</epage><pages>338-345</pages><issn>0385-0110</issn><eissn>1880-408X</eissn><abstract>The acid conditioning effects of minocycline on the root surface with mechanical root cleaning were investigated in this study. Root surface specimens were randomly assigned to scaling group (control), polishing group (polish), superficial debridement group (SL) and deep debridement group (DL) with minocycline solution (10mg/ml). The antimicrobial activities of minocycline solution (10mg/ml, 10min) against P. gingivalis, by moniforing penetration rate and attachment rate were evaluated. The results showed that all groups possessed antimicrobial activity against P. gingivalis on days 0 and 7 after root conditioning with minocycline solution (10mg/ml, 10 min). Especially, DL group exhibited significantly higher antimicrobial activity (Day 0: average 94.8 unit [p<0.01], Day 7: average 54.1 unit [p<0.05]). The penetration rate to root surfaces were significantly higher in the DL group (42.7. μm) and in the SL group (21.5. μm) (p<0.01). In the attachment rate, the SL 92.8% and DL groups 97.2% were significantly higher than other groups (p<0.01). These results suggest that minocycline root conditioning will be expected on the cementum surfaces. J. Jpn. Soc. Periodontol., 41: 339-346, 1999.</abstract><pub>JAPANESE SOCIETY OF PERIODONTOLOGY</pub><doi>10.2329/perio.41.338</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 1999/09/28, Vol.41(3), pp.338-345 |
| issn | 0385-0110 1880-408X |
| language | jpn |
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| source | J-STAGE Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | antibial substantivity minocycline periodontally involved root surfaces root conditioning |
| title | Basic study of the Effects of Minocycline HCl on Periodontally-involved Root Surfaces |
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