Clinical Evaluation of PMG on Gingivitis, Periodontitis and Stomatitis

The purpose of this study was to evaluate the clinical effects of Periodontitis-medicinal gel PMG), consisting of Dipotassium glycyrrhizinate, (Allantoin, Hinokitiol, Cetylpyridinium chloride etc. on several types of gingivitis, periodontitis and stomatitis. A total of 93 patients with gingivitis or periodontitis were randomly selected for this study from the three institutions involved. Another 42 patients with stomatitis were also examined in two institutions. Following PMG application to gingival tissues, clinical findings were examined at weekly intervals for 4 weeks. Analysis of variance was performed to determine the significance of differences between subjects, as well as the durations of post-treatment periods. After making a comparison between baseline and final data, total improvement rates were calculated. The results are summarized asfollows: 1) Seventy six percent of gingivitis andperiodontitis patients showed at least moderate improvement, 32% of these cases having marked improvement as compared to their baseline conditions. In addition, 73% of cases experienced sufficient amelioration of their gingivitis orperiodontitis for PMG to be judged effective. All patients suffering from stomatitis demonstrated moderate improvements with PMG being consideredeffective in98% of cases. 2) During these experiments, four patients with gingivitis or periodontitis and two with stomatitis showed local side effects consisting of temporary stimulation. However, these occurrences were accidental and had so systemic effects. These results indicate that PMG is useful for treating gingivitis, peridontitis and stomatitis.