Protection of Escherichia coli against Radiation Damage by 2-Methyl-1,3-Cyclohexanedione and Some Related Compounds

2-Methyl-1,3-cyclohexanedione has been found to protect Escherichia coli against both the inactivating effects of ultraviolet light and ^{60}{\rm CO}\text{-induced}$ lethality. Of a number of structurally related compounds tested, only 1,3-cyclohexanedione and 5,5-dimethyl-1,3-cyclohexanedione prote...

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Veröffentlicht in:	Radiat. Res., 34: 79-86(1968) 34: 79-86(1968), 1968-04, Vol.34 (1), p.79-86
Hauptverfasser:	Pittillo, Robert F., Lucas, Mary B.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3-CYCLOHEXANEDIONE, 2-METHYL-/radioprotective effects of, on Escherichia coli, $gamma$ and uv 1,3-CYCLOHEXANEDIONE, 5,5-DIMETHYL-/radioprotective effects of, on Escherichia coli, $gamma$ and uv 1,3-CYCLOHEXANEDIONE/radioprotective effects of, on Escherichia coli, $gamma$ and uv BACTERIA Chemical suspensions CHEMICALS COBALT 60 Cobalt Isotopes Cultured cells CYCLOALKANES DETERMINATION DRUGS EFFICIENCY Escherichia coli Escherichia coli - radiation effects GAMMA RADIATION GAMMA RADIATION/effects on Escherichia coli, protective effects of 1,3-cyclohexanedione and methylated derivatives against cobalt-60 GAMMA SOURCES HEXANE Hydrates Irradiation KETONES METHYL RADICALS N28510 -Life Sciences-Medicine-Protective Substances Radiation damage RADIATION EFFECTS RADIATION INJURIES RADIATION PROTECTION Radiation tolerance Radiation-Protective Agents - pharmacology SCHIZOMYCOTA/Escherichia coli, radiation effects on, protective effects of 1,3-cyclohexanedione and methylated derivates against $gamma$ and uv ULTRAVIOLET RADIATION ULTRAVIOLET RADIATION/effects on Escherichia coli, protective effects of 1,3-cyclohexanedione and methylated derivatives against cobalt-60 Ultraviolet Rays USES
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Zusammenfassung:	2-Methyl-1,3-cyclohexanedione has been found to protect Escherichia coli against both the inactivating effects of ultraviolet light and ^{60}{\rm CO}\text{-induced}$ lethality. Of a number of structurally related compounds tested, only 1,3-cyclohexanedione and 5,5-dimethyl-1,3-cyclohexanedione protected Escherichia coli against radiation effects. The mechanism(s) by which the compounds act are unknown.
ISSN:	0033-7587 1938-5404
DOI:	10.2307/3572459