Reactions of Human Sera to Avian Adenoviruses and Newcastle Disease Virus

The sera of two human populations were examined for antiviral reactions to avian adenoviruses and to Newcastle disease virus (NDV). Group I had close contact with poultry; Group II had limited association. None of the sera reacted with the avian adenoviruses used. Sera of Group I individuals had a h...

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Veröffentlicht in:	Avian diseases 1971-10, Vol.15 (4), p.781-788
Hauptverfasser:	Miller, Louise T., Yates, Vance J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - immunology Animals Antibodies Antibodies - analysis Antigens, Viral Aviadenovirus Chick Embryo Culture Techniques Embryos Environmental Exposure Hemagglutination Inhibition Tests Hemolytic Plaque Technique Humans Immune Sera Infections Kidney cells Mumps Mumps virus - immunology Neutralization Tests Neutralizing antibodies Newcastle disease Newcastle disease virus Newcastle disease virus - immunology Poultry Diseases - immunology Virus Cultivation Viruses Zoonoses
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Zusammenfassung:	The sera of two human populations were examined for antiviral reactions to avian adenoviruses and to Newcastle disease virus (NDV). Group I had close contact with poultry; Group II had limited association. None of the sera reacted with the avian adenoviruses used. Sera of Group I individuals had a high frequency of NDV hemagglutinin inhibitory (HI) activity; Group II sera showed no such reactions. Sera of both groups showed a low frequency of reactors having NDV neutralizing antibody. Neutralizing activity could not be related to HI activity of the sera. The HI activity observed was apparently not due to cross reactions with mumps antibody.
ISSN:	0005-2086 1938-4351
DOI:	10.2307/1588867