Discussion of: Fitting Systems of Linear Differential Equations Using Computer Generated Exact Derivatives

Discussion of: Fitting Systems of Linear Differential Equations Using Computer Generated Exact Derivatives

Dr. Jennrich and Dr. Bright deserve high praise for producing an ingenious and eminently executable idea in this area of exponential curve fitting. Upon reading their paper one main question comes to mind. To what extent does our estimate of the system parameter vector depend upon the compartment in...

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Veröffentlicht in:Technometrics 1976-11, Vol.18 (4), p.393-399
1. Verfasser: Wiggins, Alvin D.
Format: Artikel
Sprache:eng
Schlagworte:
Analytics
Computer systems
Covariance matrices
Differential equations
Excretion
Least squares
Matrices
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Beschreibung
Zusammenfassung:Dr. Jennrich and Dr. Bright deserve high praise for producing an ingenious and eminently executable idea in this area of exponential curve fitting. Upon reading their paper one main question comes to mind. To what extent does our estimate of the system parameter vector depend upon the compartment in which the data are generated? Section 1 will be devoted to an examination of this question.
ISSN:0040-1706
DOI:10.2307/1268654