THE SALT DISCHARGE OF AN ISOLATED MYELINATED NERVE FIBRE OF TOADS

1. The salt discharge of isolated single myelinated nerve fibres of the sciatic nerve-sartorius muscle prepations of the Japanese toads has been studied. 2. The denuded part of the nerve produced active salt discharge. 3. It was difficult to make the isolated single myelinated nerve fibre produce salt discharge. 4. The nerve reduced to several nerve fibres produced the salt discharge as well as the denuded part of the nerve. 5. The denuded central site of the single nerve fibre exhibited the salt discharge in all examples, and it was confirmed, that most nerve fibres in denuded part of the nerve produced salt discharge. 6. The reason why isolated single muscle fibres or single nerve fibres never produce salt contraction or salt discharge, was discussed. It was concluded that the absolutely intact state of a muscle or nerve fibre is necessary to produce salt contractions of muscle or salt discharge of nerve.